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Conclusion: The presence of hepatic steatosis does not alter hepatic glucose metabolism in response to glucagon and insulin in concentrations intended to mimic postprandial conditions
Another favorable characteristic of the DPP-4 inhibitors is their efficacy and safety profile in patients with impaired renal function
The ADA recommends considering initial dual therapy in individuals with an A1C greater than 9.0%
Efstratiadis et al
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