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Mechanistic work shows it counters oxidative stress by boosting superoxide dismutase and catalase activities
A double-blind, placebo-controlled trial in 90 HIV-positive patients with symptomatic distal symmetrical polyneuropathy found no benefit of intramuscular injection with 1 g/day of ALCAR for two weeks in the intention-to-treat analysis, but there was some pain relief in the group of 66 patients who completed the trial (84)
Parasa VR, Muvva JR, Rose JF, Braian C, Brighenti S, Lerm M
The authors declare that they have no competing interests
Before treatment, a thorough diagnostic and analytical evaluation is carried out, including specific tests to quantify the accumulated heavy metal burden, allowing for a customized and optimized therapeutic plan
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