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Its not approved for use as a weight loss treatment, for treating Type 1 diabetes, diabetes prevention, or metabolic syndrome alone
"FDA information, side effects, and uses / Accutane (isotretinoin): Drug Interactions "
An early study[12] measured an average bioavailability of 79% and a recent study[13] found a range 63%89%
Patients often report fewer fluctuations in hunger compared to oral formulations
Signal Transduct Target Ther 9:211
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