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New evidence suggests trizepatide (Zepound/Mounjaro) produces the largest weight loss on average, outperforming semaglutide in trials

Most patients begin to see more noticeable weight changes as they move into higher doses in the second or third month

Maximizing results requires attention to several other factors

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We found that HDL cholesterol and LDL cholesterol levels were higher and HbA1c levels lower in ALT responders than in non-responders