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Glucagon-like peptide 1 (GLP-1) is an incretin hormone with 30 amino-acid secreted by duodenal L-cells

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We demonstrated that in GLUTag cells, a high glucose level with L-glutamine stimulates GLP-1 secretion through a synergistic effect rather than cAMP amplification, and that a high glucose level potentiates L-glutamine-Gs activation in GLP-1 secretion

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