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Journal of Thoracic and Cardiovascular Surgery 169: e18, 2025
The effectiveness depends on what is being combined and which problem each treatment is intended to address
However, like any supplement, some people may experience mild side effects especially when starting out or taking high doses: Nausea or stomach upset: most common, usually passes after the first week Diarrhea or loose stools: reduce dose if this happens Fishy body odour: reported by some users, especially at high doses Headache: mild and temporary in some cases Restlessness or difficulty sleeping: avoid taking it late in the evening Safety Note: The European Food Safety Authority (EFSA) has declared L-carnitine safe at doses up to 3,000 mg/day for healthy adults
W.Roel-SantosS.MorrisM.EvansM.AlminanaD.GuarenteL.et al (2017)
In Parkinson's disease, dopamine-producing neurons in an area of the brain called the substantia nigra die off as a result of free radical-based damage
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