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Cautious use of parenteral cyanocobalamin is also recommended in patients with renal impairment, including premature neonates, because of the possibility of greater aluminum accumulation, which may cause central nervous system and bone toxicity
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Siebert AK, Obeid R, Weder S, Awwad HM, Sputtek A, Geisel J, Keller M
By age 50, you have about half the NAD+ you had at 20
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