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Previous clinical trials that investigated the safety and efficacy of semaglutide did not report significant vision complications except for the SUSTAIN-6 trial and a subsequent meta-analysis of 23 trials, which reported a higher risk of diabetic retinopathy complications in patients receiving semaglutide
doi:10.1098/rstb.1982.0093
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SGLT2 inhibitors and metformin are often used alongside GLP-1 therapy because they work through distinct mechanisms, offering additional benefits like weight loss and improved cardiovascular health
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