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Dietitians can provide personalised advice, taking into account your medical history, medication regimen, and weight loss goals, ensuring that your nutritional strategy supports both safety and efficacy during GLP-1 treatment
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It works the same way mechanistically, activating the GLP-1 receptor to reduce appetite, slow gastric emptying and improve insulin sensitivity, but the small molecule structure means it can be taken orally with fewer absorption constraints. In trials, orforglipron lowered blood sugar and produced meaningful weight loss in people with obesity and in those with type 2 diabetes, says LaValle
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Over timeparticularly as patients transition from the active-weight-loss phase to long-term maintenancethe psychological burden of ongoing injections can become more apparent, Akshay Jain, a clinical instructor at the University of British Columbia, told me
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