Stahl quote: "Follow the FDA label and never get anybody better" [22:10] When GLP-1s aren't appropriate [24:01] Case study: patient on paliperidone gaining weight despite tirzepatide [25:52] Discovery of nucleus tractus solitaris [28:26] The "are we allowed to prescribe this?" debate [29:10] Valproic acid, propranolol, and scope of practice [30:01] Bipolar disorder, obesity, and mood episode frequency [30:49] Moving beyond the monoamine hypothesis [31:19] UK paper: no proof depression is serotonin deficiency [33:23] Alternative treatments: TMS, ketamine, GLP-1s [34:03] Dr
Regarding the effect of the GLP-1 agonist, since it suppressed the expression of liver lipid synthesis genes FAS and SCD1, and consequently reduced liver triglyceride levels, its effect could be confirmed without measuring protein levels
At this time, continuing GLP-1s after pregnancy is confirmed is not recommended for two main reasons: Weight loss during pregnancy is not advised
Robison, MD, a board-certified cardiologist at Tri-City Cardiology Consultants in Mesa, Arizona
[Read More] Johansen PB, Nowak J, Skjaerbaek C, Flyvbjerg A, Andreassen TT, Wilken M, Orskov H