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Similarly, astrocytes were found to inhibit OPC differentiation and disrupt remyelination by releasing chondroitin sulfate proteoglycans into the ECM in primary mixed glial cell cultures from mice (Keough et al., 2016)
The molecule is small, cheap to synthesise, and would be difficult to defend commercially
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In contrast, the cost of generic metformin ranges between $15-$20 per month for most people
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