Researchers with a history of pancreatitis, medullary thyroid carcinoma, or MEN2 syndrome should avoid both compounds due to the GLP-1 receptor activation component
They are found in three isoforms and amongst them SOD1 (Cu/Zn-SOD), a predominant oxygen radical scavenger, is localized in the cytoplasm, mitochondrial intermembrane space, nucleus, and lysosomes, whereas SOD2 (Mn-SOD) and SOD3 (Cu/Zn-SOD) are localized in the mitochondrion and extracellular matrix respectively [81, 82]
Oral and Liposomal Supplementation Oral supplementation is a different story
However, Carnitine does still have some use cases as a sports supplement for its ability to potentially improve recovery, reduce oxidative stress, and boost endurance performance
ALA is considered an effective treatment for diabetes