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301 Platelets regulate inflammatory responses by interacting with monocytes through CD40L/CD40 and P-selectin/PSGL-1 and forming platelet-monocyte aggregates (PMA), which can serve as markers of platelet activation and monocyte inflammatory response and enhance the inflammatory response and phagocytic ability of monocytes, making them more effective in clearing pathogens and cellular debris

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Levothyroxine is safe in pregnancy but often requires dose increases with more frequent monitoring

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If you have sub-optimal levels with symptoms, its worth a trial of B12 even if your serum B12 levels are normal

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