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The consequence is that we cannot confidently answer basic clinical questions: What is the maximum tolerated dose in humans
We first titrated an extensive range of concentrations of each dimeric macrocycle to determine the optimal concentration to induce proliferation in normal human epidermal keratinocytes (NHEK)
Excess B12 is excreted through urine as a water-soluble vitamin, reducing the risk of toxicity
Health benefits 1
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