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B activation and suppresses the release of TNF-?, IL-1?, and IL-6, decreasing chronic low-grade inflammation linked to aging and tissue degeneration 4
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Whilst vitamin B12 toxicity is exceptionally rare, very high levels from supplements or injections have been associated with skin reactions such as acne-like eruptions
If the primary benefit is energy improvement that could be achieved with $15/month oral B12 plus a multivitamin, the injection may not be cost-justified
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