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Ikizler TA, Kramer HJ, Beddhu S, et al
The review documented GLP-1s rapid inactivation by DPP-4 even before the hormone has left the gut raising the hypothesis that GLP-1s actions may be partially transmitted via sensory neurons in the intestine and liver expressing the GLP-1 receptor rather than solely through systemic endocrine circulation
Results: The number of physical activity-related clinically significant or severe hypoglycaemic episodes was low in all trials, except ONWARDS 4 (basal-bolus trial)
NEJM, 2022
Mt s thuc/hot cht/tho dc c bit l c tng tc vi Semaglutide c th lm h ng huyt nghim trng gm: Insulin Sulfonylureas Acid alpha-lipoic Dc liu nh xng rng l gai, dy tha canh, mp ng, chui, du tm, Semaglutide lm chm thi gian lm rng d dy v c th nh hng n s hp thu ca mt s thuc ng ung
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