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Though the absolute risk of GLP-1 related aspiration during intubation is still low, case studies of large volume emesis in patients who fasted 20 hours have been concerning enough to prompt the American Society of Anesthesiology to issue a guidance suggesting holding GLP-1 agonists prior to elective intubations4,5

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Paracetamol also acts in modulating the endogenous cannabinoid system in the metabolized form of AM404

J Clin Pharmacol 45(9):10321037 Kothare PA, Linnebjerg H, Skrivanek Z, Reddy S, Mace K, Pena A et al (2007) Exenatide effects on statin pharmacokinetics and lipid response