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By improving insulin sensitivity, weight loss treatment lowers the overall pain threshold and reduces the concentration of inflammatory markers circulating in the blood
Classification was performed using an initial automated pass followed by clinical expert adjudication
Metformin is a widely prescribed, first-line oral antidiabetic agent that acts primarily through activation of AMP-activated protein kinase (AMPK), a key regulator of glucose metabolism, insulin sensitivity, and inflammation 13,14
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