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This susceptibility is compounded by impaired redox homeostasis and multiple pathogenic factors: i) dysfunctional protein clearance mechanisms involving PTEN-induced kinase 1 (PINK1), Parkin, and -synuclein proteostasis

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Similarly, if injection site reactions become progressively worse rather than improving, show signs of infection (increasing warmth, spreading redness, pus, or red streaking), or fail to resolve within several days, medical assessment is warranted

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Retatrutide does not protect against this