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Moreover, supplementation with Lactobacillus plantarum (DP189) and GOS restored gut microbial composition, improved gut and BBB integrity, reduced cortical inflammation and elevated acetylcholinesterase activity, reversing anxiety and depression-like behaviors in mice (Wang J

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Science 384:93100 stvik AE, Granlund AB, Bugge M, Nilsen NJ, Torp SH, Waldum HL, Dams JK, Espevik T, Sandvik AK (2013) Enhanced expression of CXCL10 in inflammatory bowel disease: potential role of mucosal toll-like receptor 3 stimulation