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Large double-blind, placebo-controlled trials are needed to understand whether folic acid supplementation late in life might help decrease age-related cognitive impairments or the risk of Alzheimers disease and other dementias

Copper deficiency has been linked to osteoporosis and bone development abnormalities in low-birth-weight infants and young children

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Evidence: A 2023 systematic review showed co-supplementation outperforms selenium alone for motility and morphology (2023 antioxidant review)

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