People carrying specific genetic variants may experience weaker satiety signals, making them prone to overeating despite adequate nutrition
Why diet matters on GLP-1s GLP-1 medications and dual incretin medications (for example semaglutide and tirzepatide) can increase fullness and slow digestion, which can reduce cravings and portion sizes, but may also trigger GI side effects like nausea, vomiting, heartburn, bloating, diarrhea, and constipation, especially during dose increases
Abstract Body-protective compound (BPC) 157 demonstrates protective effects against damage to various organs and tissues
doi: 10.1210/mend.9.5.7565802 81 LalloyerFPedersenTAGrossBLestavelSYousSVallezEet al
Gastrointestinal side effects of the non-peptide GLP-1 receptor agonists: A systematic review and meta-analysis