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[12] Gastric acid-suppressing agents (proton-pump inhibitors and H-receptor antagonists) diminish dietary B12 liberation from protein complexes, a pharmacodynamic interaction that can exacerbate underlying deficiency
This ensures you do it safely and correctly
But some will notice side effects, minor or annoying, yet not dangerous
Pancreatic Insufficiency: The pancreas helps with B12 absorption, and not enough of it can cause deficiency
B12 is safe on its own, but a few conditions call for extra care, which is why a provider reviews your history before treatment: Leber's hereditary optic neuropathy, a rare inherited eye condition, where certain forms of B12 may be a concern for the optic nerve
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