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Prior to the approval of Wegovy HD, the highest approved dose of semaglutide injectable for weight loss was 2.4 mg, which is also indicated, along with a reduced calorie diet and increased physical activity, to reduce the risk of major cardiovascular events such as death, heart attack, or stroke in adults with known heart disease and with either obesity or overweight
Instead, there are some international reports of serious side effects
The most reliable indicator is reduced effectiveness
Hector Perez, MD, a bariatric surgeon and an advisor at BestSurgeons.com, an online database that helps patients in the US and Mexico locate qualified surgeons, agrees that GLP-1 patches are unlikely because the drug's molecules are so large
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