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Strong evidence Peptide immunotherapy (allergen-derived peptides) has the strongest evidence base
Getting the dose right is key to avoid giving too little or too much vitamin B12
Lyophilized (freeze-dried) powder: Room temperature storage: stable for weeks to months depending on peptide Refrigerator storage (2-8 C): stable for months to over a year Freezer storage (-20 C): stable for years in some cases Keep sealed, dry, and away from light Moisture is the primary enemy of lyophilized peptides Reconstituted solution: Must be refrigerated at 2-8 C at all times Typical stability: 4-6 weeks for most peptides Never freeze reconstituted solutions Use bacteriostatic water (not sterile water) for multi-use vials Each needle puncture introduces contamination risk The difference in stability is dramatic
Many do well on oral supplements, but someone who is already symptomatic and confirmed low may recover faster with injections before switching to oral maintenance
This skin darkening is generally reversible with the help of B12 shots
