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Yes - a 2020 meta-analysis of 37 studies in Obesity Reviews found L-carnitine supplementation (2000mg/day) produced modest but significant reductions in body weight and fat mass compared to placebo
He is much more comfortable, has more energy, isn't near as starving all the time, and is loosing his fat pockets
In the genes coding for these enzymes, several single nucleotide polymorphisms have been described
Corrales FJ, Perez-Mato I, Sanchez del Pino MM, Ruiz F, Castro C, Garcia-Trevijano ER, Latasa U, Martinez-Chantar ML, Martinez-Cruz A, Avila MA, Mato JM: Regulation of mammalian liver methionine adenosyltransferase
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