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Figure 5 illustrates the antidiabetic mechanism of polyphenols in the human body, showing deconjugation in the gastrointestinal tract, absorption, hepatic portal circulation, reconjugation in the liver, biliary excretion, renal excretion, and microbial deconjugation in the colon, ultimately leading to fecal excretion
So not only does excess weight lead to insulin resistance, which increases the risk of conditions like diabetes and heart disease, but inflammation as well, which can play a role in the uncontrolled growth of cells that lead to tumors, all of which can drastically lower our life expectancy
2.3%) and there was no difference in the percentage of participants with acute pancreatitis or malignant neoplasms between the two groups [110]
Research shows that wholegrain alternatives lower blood sugar spikes and increase feelings of fullness longer [7]
It is worth noting that fatigue may also be coincidental and unrelated to GLP-1 therapy, arising from underlying conditions such as anaemia, thyroid dysfunction, depression, or sleep disorders
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