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The body uses several coordinated mechanisms to make this happen: Relaxation of the gastric fundus leads to increased gastric compliance Inhibition of antral contractility reduces propulsive forces Increased pyloric tone creates greater resistance to outflow [2] Research points to the vagal nerve pathway as the main route for this action
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The opioid antagonist naloxone appears to block some of DSIPs effects, so combining these would likely negate DSIPs benefits
The pharmacokinetic features of AC after a single intravenous dose can be understood using a two-compartmental pharmacokinetic model
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