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Moreover, phospho-BCL-XL (Ser62) stabilizes G2 arrest by binding to and co-localizing with Cdk1 (cdc2) in nucleolar structures to avoid rapid nucleolar disassembly associated with mitosis onset, playing an unexpected role in the G2 phase checkpoint downstream of DNA damage distinct from its anti-apoptotic function 22

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1 Introduction Glucagon-like peptide-1 (GLP-1), a hormone derived from the intestine, is released after eating and stimulates insulin secretion from the pancreas in a glucose-dependent manner ( With the alarming increase in the prevalence of type 2 diabetes (T2D) and its associated complications, the need for effective therapeutic strategies have become increasingly urgent ( Studies have shown gastrointestinal disturbances as the most common adverse drug reactions (ADR) associated with semaglutide

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Advances in Nutrition, 15(1), 100121

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