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Angiotensin-converting enzyme 2 is a functional receptor for the SARS coronavirus
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The implementation of a small-volume, whole blood stimulation assay for the assessment of vaccine antigen-specific responses that can be set up at the trial site using minimal equipment, followed by sample preservation in RNA stabilisers and storage or transfer to the investigating laboratory for downstream processing, facilitates immunogenicity testing in clinical and field trials
Standard and sample cytokine concentrations were then calculated using the Bio-Rad Bio-Plex 200 software and results displayed as pg of analyte per mL of sera
