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Description

Compounds that trigger signalling cascades can produce effects that persist well after the molecule is undetectable

Safety signals are generated from several sources such as spontaneous reports, clinical studies and the scientific literature

However, the effects vary considerably between individuals

Choi, T

Analysts were hoping for a safety profile similar to what was achieved in Phase II but an abnormal sense of touch, called dysesthesia, has emerged in the late-stage TRIUMPH-4 trial

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