Imbalance can manifest as mild GI effects or fatigue patterns in animal models
Third, the paradoxical behavior of p53 mutants deserves our attention
Prior to the relatively recent description of the microbiota as a potent modulator of a range of physiological and psychological factors, even controversially termed as an extra organ (as discussed by Riccio and Rossano, 2020), the GIT bacteria were largely ignored, even in studies of digestion
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The new 5-HT hypothesis of depression: Cell-mediated immune activation induces indoleamine 2,3-dioxygenase, which leads to lower plasma tryptophan and an increased synthesis of detrimental tryptophan catabolites (TRYCATs), both of which contribute to the onset of depression