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While the aim of this article is not to review these and other considerations in detail, the box below represents a compilation of a few unanswered questions that could guide further academic and clinical discourse in this area
Intestinal enzymes break down the glutathione tripeptide before it crosses the intestinal barrier, limiting the amount reaching systemic circulation and target tissues
For example, supplementing with MSM significantly reduced inflammation in mice with stomach ulcers by inhibiting the release of inflammatory cytokines including TNF- and IL-6, as well as increasing glutathione levels ( Another study in 40 physically active men showed that taking 3 grams of MSM before exhaustive exercise decreased the release of inflammatory cytokines and prevented the over-stress of immune cells, compared to a placebo ( Summary MSM may reduce the release of molecules associated with inflammation, such as TNF- and IL-6, as well as boost levels of the powerful antioxidant glutathione
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