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1170 HK, the enzyme that initiates glycolysis through glucose phosphorylation, is competitively inhibited by 2-deoxyglucose (2-DG), which structurally resembles glucose and binds to HK2, thereby hindering its activity through the accumulation of phosphorylated 2-DG

This mechanism leads to enhanced insulin secretion, decreased glucagon release, and slowed gastric emptyingall contributing to lower blood glucose levels and reduced appetite

Este proceso es fundamental para el metabolismo energtico, especialmente en tejidos con alta demanda como el msculo esqueltico y el cardaco

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