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The HARMONY Outcomes CVOT (which only included subjects with established CVD) similarly showed a 22% CV risk reduction with albiglutide vs placebo (hazard ratio 0.78) [37], and the REWIND CVOT showed an identical 13% effect size across subgroups with and without established CVD (hazard ratio 0.87) [38]
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While the lyophilised powder form is more resilient than reconstituted solutions, it is still vulnerable if stored without proper safeguards
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Sterile water has no preservative in it
