Understanding the relationship between Mounjaro and orthostatic hypotension is essential for safe prescribing, particularly in older adults, those with autonomic neuropathy, and patients taking multiple antihypertensive agents
Furthermore, palatable food-mediated CPP was increased by ghrelin, but blocked by a GHS-R1a antagonist or genetic deletion of GHS-R1a or ghrelin (Egecioglu et al., 2010
The ultimate therapeutic dose should be achieved on the basis of both tolerability and clinical response [seeWarnings and Precautions (5.14),Use in Specific Populations (8.5), andClinical Pharmacology (12.3)]
While a link between Ozempic and stomach paralysis has not been established yet, GLP-1s are not recommended for people who already have gastroparesis
Some of these studies are happening at VCU