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Avoid in active malignancies, the protocol shouldnt exacerbate undiagnosed tumors
Visible fine line reduction and improved elasticity typically appear at 4 to 8 weeks
The amount delivered per spray depends on the spray device, solution concentration, and consistency of administration
Because the use of ASL MRI in relation to AD neuropathology is still very new, there is a need to validate these metrics with other biomarkers of AD and to characterize disease-specific cerebral blood flow changes longitudinally (Montagne et al., 2016a)
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