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This demonstrated the antagonistic effect while also providing evidence for the crucial role of GIP receptor signaling in potentiating the insulin response to oral glucose ( Alongside studies of GIP(7-30)NH 2 , other truncated forms: GIP(10-30), GIP(6-30)NH 2 and GIP(7-30) were characterised as GIP receptor antagonists with the ability to block GIPs activation of the GIP receptor in vitro

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