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The clinical evidence base for these agents, both individually and in combination, is still emerging

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Although LipRSV treatment has not been widely studied in animal models of autism, one study showed that RSV treatment prevented changes in neuronal organization and the number of GABAergic interneurons in the frontal cortex and hippocampus of VPA-exposed rats, suggesting that RSV may have protective effects in specific brain regions (Santos-Terra et al

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Furthermore, it has been found that modulation of the Nrf2 signalling pathway by triterpenoids compounds results in a significant increase in survival in the SOD1 G93A mouse model of ALS, thereby indicating that activation of Nrf2 has a neuroprotective effect [268]

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