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10.1002/ptr.2021 178 HallacliE.KayatekinC.NazeenS.WangX

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Individual Results May Vary Responses to GLP-1 therapy can vary from person to person

GLP-1 receptor activity GLP-1 receptor activation can: Reduce appetite Increase feelings of fullness Slow stomach emptying Support glucose-dependent insulin release Reduce food intake This common GLP-1 activity helps explain why nausea, diarrhea, vomiting and constipation appear across all three drugs

Kidney Disease Patients with acute or worsening kidney disease are advised against Semaglutide