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Most people notice improvements in energy and symptoms within a few days, but full benefits may take a few weeks depending on how low your levels were before treatment
Sucic M et al
Those who follow a strict vegetarian or vegan diet without compensating with B12 fortified food for example ( vitamin B12 binds to animal proteins), or have low vitamin B12 levels due to a health condition that might affect vitamin B12 release and absorption, might have difficulty reaching their vitamin b12 requirements
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