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These studies in mice evaluated dosing at an incredibly wide range (2.5-40mg/kg) with 5mg/kg being the median dose

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Because Vitamin B12 has a unique role in the production and regeneration of cells, this means that its important to have healthy levels of this vitamin to have healthy skin, hair and nails

Those on Certain Medications : Some medications, such as metformin (for diabetes) or proton pump inhibitors (for acid reflux), can interfere with B12 absorption