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The sensors can detect when: The packaging is opened The adhesive cover is removed The patch has been applied The patch is removed from the skin A wireless MCU within the patch switches between operating modes and sends usage signals via Bluetooth Low Energy that are interpreted by Ategenos cloud software
Here's the definitive quick reference: SIGNATURE TOXICITIES & ANTIDOTES: Cyclophosphamide = Hemorrhagic Cystitis MESNA (2-Mercaptoethane Sulfonate) Methotrexate = Myelosuppression Leucovorin (Folinic Acid) Rescue Doxorubicin = Cardiotoxicity Dexrazoxane (Cardioprotective) Cisplatin = Nephrotoxicity, Ototoxicity Amifostine (Cytoprotective) Bleomycin = Pulmonary Fibrosis (No antidote Prevention) Vincristine = Peripheral Neuropathy (No antidote Dose limiting) 5-FU = Palmar-Plantar Erythrodysesthesia (Hand-Foot Syndrome) CLASSIFICATION: Cell Cycle Specific: MTX (S), 5-FU (S), Vinca alkaloids (M), Taxanes (M) Cell Cycle Non-Specific: Cyclophosphamide, Doxorubicin, Cisplatin Mnemonic: "MESNA = Makes Cyclophosphamide Safe (NA)" One topic
Metabolic reprogramming: a bridge between aging and tumorigenesis
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Signaling and Synthesis: The prolonged, unbound presence of IGF-1 LR3 in the bloodstream maximizes the anabolic signaling effect on muscle tissue, activating intracellular signaling pathways that promote protein synthesis and muscle fiber hypertrophy (increase in cell size)
