Inflamed synovium produces prostaglandins, leukotrienes, ROS, cytokines, chemokines, and adipokines, all of which contribute to cartilage breakdown and further exacerbate inflammation (Scanzello and Goldring, 2012)
At the same time, the significant effect of Polygala tenuifolia in the treatment of insomnia, amnesia, and depression has gradually been unveiled [9, 10], and it can improve insomnia by regulating the GABAergic system to achieve sedative and hypnotic effects [11]
And the last but not least, it's not a biological markers per se, but it's more towards my function test
Immune Boost Protocol Building on the standard formulation, the immune boost variation adds zinc sulphate (10mg), selenium (200mcg), and additional vitamin C
Heat stress induces a three-phase thermoregulatory response in different hot and humid environments in rats