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It has been most extensively studied for diabetic peripheral neuropathy, blood sugar control, and weight loss
Activation of the nuclear receptor FXR improves hyperglycemia and hyperlipidemia in diabetic mice
Who should consider tirzepatide with B12 and who should avoid it Ideal candidates for tirzepatide with B12 include adults with obesity (BMI 30) or overweight with comorbidities (BMI 27 with conditions like type 2 diabetes, hypertension, or dyslipidemia)
An alternative strategy of starting the diagnostic investigation with mRNA sequencing has also been recommended, particularly because of the delay in diagnosis that can occur when glutathione synthetase deficiency results from a splice site mutation (02)
Stemler, K
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