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Roles for glutathione transferases in plant secondary metabolism
Targets for antibody drug conjugates approved or in development in small cell lung cancer
This can contribute to fatigue, digestive issues, and metabolic disorders
Pharmacol., Vol
138,139,140 These transport mechanisms, often coupled with vesicular trafficking and metabolic reprogramming, significantly reduce intracellular drug accumulation, attenuate target engagement and contribute to immune evasion, collectively undermining therapeutic efficacy
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