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Ceruloplasmin synthesis drops measurably in advanced liver disease

CoQ10 is not currently recommended in UK clinical guidelines (NICE) for managing chronic kidney disease or liver conditions and should not replace standard medical care

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It is the most abundant intracellular antioxidant in human cells and is often called the "master antioxidant" for its central role in redox homeostasis, enzymatic detoxification, and protection against oxidative damage