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The plasma level of L-Cn in the HBeAg + CHep group who had flared ALT was significantly elevated than the HBeAg - CInf, HCs, and HBsAg loss groups ( Figure 1A )
Kim Y, Keogh JB, Clifton PM
There has been evidence that intraperitoneal injection of Ex-4 protected against ischemia-induced neuronal apoptosis potentially by upregulating expression of the GLP-1R mainly in GABAergic interneurons or astrocytes in the hippocampal CA1 region of gerbils (131) proved the neuroprotective efficacy of intracerebroventricular injection (i.c.v.) of Ex-4 exerted after transient ischemia/reperfusion in rats and first suggested that Ex-4 played a neuroprotective role probably by stimulating the GLP-1R/-endorphin signal pathway in hippocampal microglia ( Another study (132, 133)
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