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S., Osborne, D., Ciancetta, A., Boison, D
These mechanisms are studied exclusively in experimental environments to better understand biochemical signaling behavior at the molecular level
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We hypothesize that (i) the slow inhibition observed in the biochemical assay with the recombinant protein with some of the compounds is due to their preferential binding to a slowly populated conformer of the NADP + -TGR(H) complex and (ii) this conformer is already populated in the worm cell interior accounting for the more rapid inhibition of TGR observed in ex vivo worms with the slow inhibitors
Sn phm ny khng phi l thuc v khng c tc dng thay th thuc cha bnh, bn vui lng s dng theo liu lng c khuyn co hng ngy
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