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Variants in FTO (the fat-mass and obesity-associated gene), GLP1R (the GLP-1 receptor gene that is the direct target of every GLP-1 compound), MC4R (a melanocortin receptor central to satiety), and TCF7L2 (a transcription factor tied to glucose handling and GLP-1 secretion) describe the metabolic terrain a clinician prescribes into
Key Points: The Wegovy pill and Wegovy shot deliver the same FDA-approved active ingredient through different administration methods
By activating GLP-1 receptors in the hypothalamus and related neural circuits, Semaglutide boosts feelings of fullness, decreases hunger, and reduces reward-driven eating
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